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1 article(s) from Petzold, Dominique

Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis

Shijie Ye,
Allison Ann Berger,
Dominique Petzold,
Oliver Reimann,
Benjamin Matt and
Beate Koksch

Beilstein J. Org. Chem. 2010, 6, No. 40, doi:10.3762/bjoc.6.40

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Graphical Abstract

Figure 1: General strategy of using a chemically aminoacylated suppressor tRNA and an in vitro translation sy...

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Figure 2: Structures of non-canonical amino acids. a. (S)-ethylglycine, b. (S)-2-amino-4,4-difluorobutanoic a...

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Scheme 1: General scheme for the synthesis of an N-(4-pentenoyl) amino acid cyanomethyl ester.

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Scheme 2: General scheme of synthesis of mono-2′(3′)-O-[N-(4-pentenoyl)aminoacyl]-pdCpAs and 2′-3′-bis-O-[N-(...

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Figure 3: Denaturing PAGE of ligation products of truncated suppressor tRNA and fluorinated aminoacyl-pdCpAs ...

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Preliminary Communication

Published 20 Apr 2010

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